Eleventh international conference on carcinogenesis and risk assessment Environmental skin carcinogenesis: UV- and chemically induced cancer Implications for risk assessment

1998 ◽  
Vol 23 (3) ◽  
pp. 131-131
Author(s):  
Thomas J. Slaga ◽  
John DiGiovanni ◽  
Andres J.P. Klein-Szanto
Keyword(s):  
Risk Assessment ◽  
Skin Carcinogenesis ◽  
International Conference ◽  
Chemically Induced

scholarly journals Effect of transgenic overexpression of BMP antagonist noggin on chemically-induced skin carcinogenesis

2020 ◽  
Vol 433 ◽  
pp. 012047
Author(s):  
A N Mardaryev ◽  
N V Mardaryeva ◽  
G A Larionov ◽  
V S Gordova ◽  
M G Terentyeva
Keyword(s):  
Skin Carcinogenesis ◽  
Chemically Induced ◽  
Bmp Antagonist

scholarly journals Slit2 promotes tumor growth and invasion in chemically induced skin carcinogenesis

2014 ◽  
Vol 94 (7) ◽  
pp. 766-776 ◽  
Author(s):  
Cuiling Qi ◽  
Haimei Lan ◽  
Jie Ye ◽  
Weidong Li ◽  
Ping Wei ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Skin Carcinogenesis ◽  
Chemically Induced ◽  
Tumor Growth And Invasion

Chemotherapeutic/chemopreventive role of retinoids in chemically induced skin carcinogenesis in albino mice

2007 ◽  
Vol 46 (11) ◽  
pp. 1160-1165 ◽  
Author(s):  
Mulazim H. Bukhari ◽  
Shahzad Shafqat Qureshi ◽  
Shahida Niazi ◽  
Mohammad Asef ◽  
Mamona Naheed ◽  
...  
Keyword(s):  
Skin Carcinogenesis ◽  
Chemically Induced ◽  
Albino Mice

scholarly journals Human papillomavirus type 38 E6 and E7 act as tumour promoters during chemically induced skin carcinogenesis

2013 ◽  
Vol 94 (4) ◽  
pp. 749-752 ◽  
Author(s):  
Daniele Viarisio ◽  
Karin Müller Decker ◽  
Birgit Aengeneyndt ◽  
Christa Flechtenmacher ◽  
Lutz Gissmann ◽  
...  
Keyword(s):  
Skin Lesions ◽  
Human Papillomaviruses ◽  
Skin Carcinogenesis ◽  
Non Melanoma Skin Cancer ◽  
Multi Stage ◽  
Chemically Induced ◽  
Contrast Exposure ◽  
Tumour Promoters ◽  
Hpv Types ◽  
E6 And E7

Many findings support a possible involvement of a subgroup of human papillomaviruses (HPVs), called cutaneous beta HPV types, in the development of non-melanoma skin cancer. The skin of transgenic (Tg) mice expressing viral oncoproteins E6 and E7 from different cutaneous beta HPV types, including HPV38, showed an increased susceptibility to UV-induced and/or chemically induced skin carcinogenesis compared with wild-type animals. In this study, we show that beta HPV38 E6 and E7 oncoproteins act as promoter and progression factors in multi-stage skin carcinogenesis, strongly cooperating with the initiator and DNA damage agent 7,12-dimethylbenz[a]anthracene. In contrast, exposure of HPV38 E6/E7 Tg mice to the promoter 12-O-tetradecanoylphorbol-13-acetate did not significantly result in the development of skin lesions. These findings further support the role of beta HPV types in skin carcinogenesis, providing additional insight into their precise contribution to the multi-step process.

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